Mutational variation of COVID-19 and the prophylaxis of its infective mode corona to human are climate dependent. The said molecular biological problem could be explained in following manner. It is proposed that transcription aspects of corona are genetic dependent and ACE is the climate based. Genetic dependence is controlled by the development of m-RNA and the release of spike proteins. ACE (Angiotensin Converting Enzyme) and the binding to spike protein possibly influence the development of infection, and the growth of existing pneumonia of the body immunologically susceptible. The global temperature, and the change of food habits, are continuously imposed by population pollution growths. Biological, chemical, nanoparticle based animate and in-animate molecules in the form of invisible Nano-dust, are entering into an individual and are responding on the basis of its responses at that moment provides the combined historical innate immunity. The response (IR) by the hosts, the cough oriented pneumococcal bacterial development and other viral infective, comorbid situation (i.e. strong resistive nature of the hosts against environment, that may support the formation of mutated m-RNA inside the Corona virus, searching time to attach spike protein on lung alveoli cells, activate ACE (Angiotensin Catalytic Enzyme, I and II), supposed to be involved to get entry into lung alveoli cells and their multiplicity. An AAIR (Antiadherent Immune Response) and bacteriophage related lytic nature of corona support hybrid mode of viral vaccine and the same would be essential to stop the propagation of corona globally. Irrespective to immune response of an individual. A combined m-RNA of Corona and r-RNA of pneumococcus lytic bacteriophage, AAIR based general body immune response could abolish corona from human race
Key words: Corona, AAIR, m-RNA and r-RNA
Prof. Brahma was (born 01-11-1946 in Bangladesh/ India), a life member LM-10671 of Indian Institute of Chemical Engineers, JU, Kolkata 700032, India and fellow of the Institution of Engineers (India), F-113278-0, 8 Gokhale Road, Kolkata 20. He was a former regular faculty of the Chemical Engineering, Dept. IIT-Khragpur-721302, India, and served the Dept as Lecturer and Sr. Scientist since 1988 and was superannuated on 2011. After that he was involved as visiting Faculty in the Institute of Genetic Engineering, Badu, Madhyagram, MACAUT affiliated, Kolkata-700128. Prof. Brahma, served also WBSC/IEI, as Honry Sec for the center and the Chemical Engineering sub-Division as Convener/Chairman, and completed around 50 national and international seminars since 2011. He was also fellow of the Max-Planck Institute (Society) (1980-1986) and recently he has been selected as a Chairman of the Chemical Engineering Sub Div., WBSC/IEI. Prof. Brahma, academically completed as topper Distinction, B.Sc ÇU,1966, B.tech,1972 M.tech,1975 The Technical University, Berlin, Germany(TUB) and Doctoral work in Max-Planck Germany )1980-1986,1986 .Since 1986 he was actively engaged as Sr. Scientist Lecturer in JU and IIT KGP , Chemical. Egg Dept. And continued till 31-10-2011.He is an expert on Bioprocess engineer, with back ground of Chemical Unit operation, Molecular Biology Environment, Bioprocess and Biotechnology. Prof Brahma completed his graduations and post-graduation from the Technical University, Berlin, Germany, 1975, Prof Brahma published more than 100 articles related to Genetic engineering, Chemical and Bio-Chemical Process Technology and three books, entitled’ Introduction to Chemical Science and Engineering (ITCSE), Molecular and Engineering Concept of Microbiology (MAECOM); and Bacterial Adherence by Lap- Lambert-Germany/USA.
Prof Brahma extensively lived and traveled most of the part of the world including USA, CHINA, EUROPE. Based on his innovative hybrid concepts of engineering he was renowned and developed different model of vaccination during pandemic against corona infection. He emphasizes that biology knowledge to all engineers are essential to design and to sustain the environment. He also emphasize, all universities and institutes n India Should work on Algae and AIO(Artificial Internal Organ) ,Evolution, Transposable Genetic Elements, (Jumping Gene). Prof. Brahma developed recently two important research environment on BNT (Bio nanotube ) and Climate Change and Microbes.
Prof Brahma received Invitation from AIChE (American Institute of Chemical Engineers) 2006, USA Florid, 2016, USA Chicago,2017 in Vancouver Canada. Prof. Brahma likes teaching, research, human interactions, Leadership and to develop Labs at world class reputation and to design Bioreactors and AIO like ÀK (Artificial Kidney). as internationally accepted published documents. Climate Change and Universal Vaccines concepts are these two-existing burning research activities.