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4th Edition of World Congress on Infectious Diseases

June 21-22, 2023 | Rome, Italy

June 21 -22, 2023 | Rome, Italy
Infection 2023

Mbida Mbida Jean Arthur

Speaker at World Congress on Infectious Diseases 2023 - Mbida Mbida Jean Arthur
university of douala, Cameroon
Title : First evidence on the circulation of trypanosoma brucei gambiense in manoka island in littoral region of cameroon: Epidemiological implications and perspectives


A survey on Human African Trypanosomiasis (HAT) is essential for prevention and preparedness for epidemics. The objective of the study was to assess the circulation of human trypanosomes and their vectors across quiescent HAT foci of the Littoral Region of Cameroon.

A descriptive study on the presence of Trypanosoma brucei gambiense and its potential vectors was carried out in Youpwe, Yabassi, Sodiko, Manoka island and Cape-Cameroon Island from February to April 2022.Tsetse flies collected from the five selected locations using pyramidal traps, were first classified by species according to their morphology, then by sub-species with Polymerase Chain Reaction Diagnostic (PCR-Diag). Trypanosoma species and sub-species were subsequently identified and genotyped using a Nested PCR.

Glossina palpalis palpalis was the unique tsetse subspecies recorded across the five locations. The tsetse infection rate by Trypanosoma ssp. varied between 5.35% in Cape-island and 35.71% in Manoka island. Three Trypanosoma species were detected: T. brucei s.l. 32/500 (6.4%), T. congolense 15/500 (3.0%), and T. vivax 8/500 (1.6%). The sub-species T. b. gambiense responsible for HAT was detected in tsetse flies from Manoka (2/150: 1.33%), whereas T. congolense consisted of T. congolense “forest” and T. congolense “savannah” types.

The presence of T. b. gambiense and T. congolense sub-species in Manoka and nearby suggests residual circulation of human and animal trypanosomes in quiescent HAT foci of the littoral region of Cameroon. The implementation of epidemiological surveillance is imperative for an efficient response in the event of an outbreak of the disease.


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