Biography:
Dr. Yen-Chin Liu received her PhD degree in 2014 from Graduate Institute of Biomedical Sciences, Chang Gung University, Taiwan. The findings reveal a novel mechanism of viruses attacking hosts whereby picornaviral polymerase (3Dpol) enters the nucleus and targets the central pre-mRNA processing factor 8 (Prp8) to block pre-mRNA splicing and mRNA synthesis. This work has been published in PLoS Pathogens.
Dr. Liu worked as post-doctoral fellow from 2014 to 2019 in Department of Microbiology, the University of Hong Kong. She identified a novel virus host interaction mediated by XRN1 in influenza virus infection. This work has been accepted by mBio.
Title : SARS-CoV-2 omicron nucleocapsid effectively suppresses interferon beta expression via interaction with host HSPA4