Title : Analysis of oral clinical manifestations and serological test results of secondary syphilis
Abstract:
Objective:
To analyze the correlation between serological test results and oral clinical manifestations of patients with secondary syphilis, and to provide reference for clinical diagnosis and treatment.
Methods:
From January 2016 to December 2020, 30 patients with secondary syphilis were treated in Nanjing Stomatological Hospital and Nanjing Stomatological Hospital, School of Medicine, Nanjing University, and they were retrospectively analyzed to investigate the correlation between oral clinical manifestations (including the number and grade of lesions) and serological test results [rapid plasma reactin ring card test (RPR) titers].
Results:
Among the 30 patients included in the study, 14 were male and 16 were female. There were 11 young people (≤44 years old), 10 middle-aged people (45-59 years old) and 9 elderly people (≥60 years old). There was no significant difference in gender distribution among different age groups (P>0.05). The oral mucosal lesions of the patients were characterized by mucosal plaques and mucositis, and the most frequent sites were lips, tongue, pharynx, palate and buccal division. Patients with high RPR titer (≥1:128) had more oral mucosal lesions and higher clinical lesion grade compared with patients with low RPR titer (<1:128), with statistical significance (P<0.05).
Conclusion:
RPR titer of secondary syphilis patients with oral mucosal lesions is closely related to the number of oral mucosal lesions and clinical lesions grade.
Audience take away:
• Introduce our research about the correlation between serological test results and oral clinical manifestations of patients with secondary syphilis.
• Provide ideas and suggestions to further study the significance of serological test in the diagnosis of syphilis
