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8th Edition of World Congress on Infectious Diseases

June 09-11, 2025 | Rome, Italy

June 09 -11, 2025 | Rome, Italy
Infection 2023

Analysis of oral clinical manifestations and serological test results of secondary syphilis

Speaker at Infection Conferences - Yuefeng Song
Medical School of Nanjing University, China
Title : Analysis of oral clinical manifestations and serological test results of secondary syphilis

Abstract:

Objective:
To analyze the correlation between serological test results and oral clinical manifestations of patients with secondary syphilis, and to provide reference for clinical diagnosis and treatment.

Methods:
From January 2016 to December 2020, 30 patients with secondary syphilis were treated in Nanjing Stomatological Hospital and Nanjing Stomatological Hospital, School of Medicine, Nanjing University, and they were retrospectively analyzed to investigate the correlation between oral clinical manifestations (including the number and grade of lesions) and serological test results [rapid plasma reactin ring card test (RPR) titers].

Results:
Among the 30 patients included in the study, 14 were male and 16 were female. There were 11 young people (≤44 years old), 10 middle-aged people (45-59 years old) and 9 elderly people (≥60 years old). There was no significant difference in gender distribution among different age groups (P>0.05). The oral mucosal lesions of the patients were characterized by mucosal plaques and mucositis, and the most frequent sites were lips, tongue, pharynx, palate and buccal division. Patients with high RPR titer (≥1:128) had more oral mucosal lesions and higher clinical lesion grade compared with patients with low RPR titer (<1:128), with statistical significance (P<0.05).

Conclusion:
RPR titer of secondary syphilis patients with oral mucosal lesions is closely related to the number of oral mucosal lesions and clinical lesions grade.

Audience take away: 
• Introduce our research about the correlation between serological test results and oral clinical manifestations of  patients with secondary syphilis.
• Provide ideas and suggestions to further study the significance of serological test in the diagnosis of syphilis

Biography:

Dr. Yuefeng Song graduated from the Medical School of Nanjing University in 2017 with a master's degree in stomatology. She is now an attending physician in the Department of Oral Medicine of the Nanjing Stomatological Hospital and is good at the diagnosis and treatment of common diseases of oral mucosa. She has published 4 papers as the first author/co-first author and participated in the compilation of 2 monographs.

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