HYBRID EVENT: You can participate in person at Paris, France or Virtually from your home or work.

6th Edition of World Congress on Infectious Diseases

June 24-26, 2024 | Paris, France

June 24 -26, 2024 | Paris, France
Infection 2024

Ahsan Ehtesham

Speaker at Infectious Diseases Conference - Ahsan Ehtesham
Hamad Medical Corporation, Qatar
Title : A rare case of aortic aspergillosis in an immunocompetent patient with no pre-existing cardiac pathology – A case report


Background: Cardiac aspergillosis is a rare form of Invasive Aspergillus infection that carries high mortality despite aggressive treatment. It usually occurs in patients with underlying cardiac abnormalities such as cardiac lesions, prosthetic valves, cardiac devices, and heart transplants. 

Case Summary: A 30-year-old male with right-sided body numbness had a CT Head revealing a suspected neurocysticercosis lesion. Initial labs showed mildly elevated CRP and normal procalcitonin. Echocardiogram found a mass on the aortic valve and a thick left atrial wall. PET CT revealed a hypermetabolic mass around the heart and aortic root. IgG4 levels were high and tissue biopsy was needed for confirmation. However, the patient developed bilateral lower limb ischemia and weakness, requiring emergency surgeries. The biopsy showed invasive aspergillosis, treated with Amphotericin B. Unfortunately, the patient deteriorated into septic shock despite treatment.

Discussion: This clinical case accentuates several challenges encountered in the management of aortic aspergillosis in a patient with a low suspicion of invasive aspergillosis. Firstly, it emphasizes the importance of considering the rare possibility of invasive aspergillosis in immunocompetent patients, even with no known risk factors. Secondly, it brings out the recognition of the rapid progression of Aspergillosis endocarditis with poor outcomes. Finally, it emphasizes that early surgical treatment and early histological diagnosis with early initiation of antifungals can save lives.


Dr Ahsan Ehtesham graduated from Dow University of Health Sciences in 2016. He is currently a resident in training in cardiothoracic surgery since 2020 at the prestigious Hamad Medical Corporation. He is an active researcher with a growing portfolio of articles, researches, and case reports. Currently he has 4 published articles, with 5 more projects underway.