HYBRID EVENT: You can participate in person at Paris, France or Virtually from your home or work.

6th Edition of World Congress on Infectious Diseases

June 24-26, 2024 | Paris, France

June 24 -26, 2024 | Paris, France
Infection 2024

Niranjan Nayak

Speaker at Infectious Diseases Conference - Niranjan Nayak
Manipal College of Medical Sciences, Nepal
Title : Bacteria or kidney stones: Which came first?


Background: Urinary Tract Infection (UTI) due to Salmonella Typhi is uncommon, though there are scanty reports of bacteriuria caused by nontyphoidal Salmonellae and other gram negative bacilli. However, cases of bacteriuria with UTI due to nontyphoidal Salmonellae were more frequently reported in the past, among individuals having urolithiasis.

Case study: We, herein, report a case of Salmonella Typhi bacteriuria with urolithiasis in a woman aged 35 years, having poor socio-economic background and coming from the rural belt of western Nepal with inadequate and hygienically unsatisfactory drinking water facility.

Results: Multiple renal stones were detected in the ultrasonography (USG) of the abdomen and pelvis advocated as part of the investigations in the management of multiple episodes of bleeding per vagina (PV), the woman was complaining of Bacterial culture of both the stone and urine sample showed the growth of Salmonella Typhi with similar antibiogram profile. Bacterial culture of both the stone and urine sample showed the growth of Salmonella Typhi with similar antibiogram profile.

Conclusion: Our report highlighted the association of renal stone with urinary excretion of Salmonella Typhi. Isolation of the organism from the crushed out material of the renal stone as well as from the urine could suggest the persistence of the organism in the stone matrix being excreted from time to time giving rise to intermittent bacteriuria. Based upon the clinical radiological and laboratory findings in the present case, an attempt has been made to unravel the poorly understood mechanism of urinary career state in Salmonella Typhi infection. 


Dr Niranjan Nayak, Professor and Head of Microbiology at the Manipal College of Medical Sciences, a 500 bedded teaching hospital in Pokhara, Nepal is a retired Professor of Microbiology from the All India Institute of Medical Sciences (AIIMS) New Delhi, India . He has 107 research publications to his credit. He participated in more than 35 national/international conferences, where he presented his research and/or chaired scientific sessions. He supervised the thesis works  of a number of PhD and MD students in Microbiology. He regularly teaches MBBS and postgraduate (MSc and MD) students. He devotes time in teaching ,research, patient care.