Title : Effect of an immunomodulator rs100 in vaccinated, unvaccinated and challenged with Mycoplasma Hyopneumoniae
Abstract:
Enzootic pneumonia is a disesease caused by M.hyopneumoniae (Mh).The immunomodulator RS-100 we used in this study is of vegetable origin. Clinical, serologic and leuko parameters in piglets treated with the RS100 and challenged with Mh. For 15 days no clinical signs were observed caused by the RS100 not the vaccination. In first w after challenge, high temp were seen in all groups. Groups A and B showed fever on days 15 to 21 PI cough started on day 15 PI and until day 21, cough and dispnea were observed. groups C and D showed fever only on days 18 to 21. The leukocyte count on group A remained normal, but groups B, C and D that received the RS 100 and the vaccine, a leukocyte count increased, to return to normal after the challenge. The best was D with RS 100 and a commercial vaccine. In the titration of antibodies groups A and B showed a weak antibody response and groups C and D a good antibody response up to week 5 and after the challenge, the readings decreased. In the antibody response also the group with a commercial vaccine and RS 100 was de best. Our results caused an increase in leucocytes. PAPIIT IN203522 and CI2412.
