Title : Strengthening four communities of practice of the one health knowledge nexus: A community-driven platform for operationalizing one health
Abstract:
One Health (recognizes the interdependence of human, animal, plant, and environment health, yet its implementation continues to face context-specific challenges. To address these barriers, the One Health Knowledge Nexus was established in 2023 in support of the Quadripartite One Health Joint Plan of Action. The One Health Knowledge Nexus connects over 2,700 stakeholders across eight Communities of Practice to strengthen countries’ capacities to operationalize one health principles and practices.
Since 2024, a dedicated project has expanded the One Health Knowledge Nexus activities in four communities of practice, using open, participatory mechanisms to promote collaborative guideline development, peer exchange through discussion boards and learning dialogues, and co-creation of context-appropriate technical resources. These activities aim to produce knowledge products that are directly relevant to country-specific needs and priorities.
Key outputs include 21 learning dialogues, 19 case studies, a conceptual framework on addressing the drivers of emerging animal and plant pests and diseases, training materials on one health return on investment, a one health policy database, one health governance monitoring and evaluation recommendations, and mapping of over 30 information and communication tools supporting one health intelligence, risk management, risk communication, and learning.
These outputs have informed policymakers in Malawi, Ghana, and Nigeria, strengthening multisectoral coordination, supporting evidence-based decision-making, and contributing to the development of costed one health national action plans. By fostering community-driven knowledge exchange and co-created resources, one health provides a scalable model for operationalizing the One Health approach to infectious disease prevention, detection, and response.

