The process of drug discovery and development for infectious diseases is a multifaceted endeavor that encompasses various stages and disciplines. Initially, researchers embark on the quest for novel therapeutic agents by identifying promising drug targets within microbial pathogens. Utilizing cutting-edge technologies such as high-throughput screening and computational modeling, scientists screen vast libraries of compounds to pinpoint potential candidates with antimicrobial activity. Subsequently, selected compounds undergo rigorous preclinical testing to evaluate their safety, efficacy, and pharmacokinetic properties. Upon successful validation, promising candidates progress to clinical trials, where their therapeutic potential is assessed in human subjects. Throughout this journey, collaboration between academia, pharmaceutical companies, and regulatory agencies is essential to navigate the complex regulatory landscape and bring effective treatments to market, addressing the urgent global need for innovative therapies to combat infectious diseases.
Title : Diagnostic approaches, predictive and prognostic assessments, monitoring, treatment & management of infectious diseases and disease prevention
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : The accelerated timeline: Human ecology, climate change, and the next global outbreak
Claudia Ferreira, Sorbonne University, France
Title : Climate change and increasing death due to resistant infection
Yazdan Mirzanejad, University of British Columbia, Canada
Title : Recurrent klebsiella pneumoniae pyogenic liver abscess: Developing a literature-informed 0–2 scoring framework from a solved index case
Martha Grace McLean, Anne Burnett Marion School of Medicine at Texas Christian University, United States
Title : Post-hysterectomy pelvic abscess mimic: An AI-assisted diagnostic stewardship workflow
Setu Shiroya, Anne Burnett Marion School of Medicine at Texas Christian University, United States
Title : Building a clinical reasoning tool from post-transplant MRSA sepsis: A mentored ai workflow
Michaela Mitchell, Anne Burnett Marion School of Medicine at Texas Christian University, United States