This year we reached 40 years since discovery of Human Immunodeficency Virus (HIV), AIDS is one of the most important pandemic infectious disease in the five last decades. No active antiretroviral therapy emerged for more than ten years. Opportunistic infections and AIDS related [....] » Read More
This meta-analysis aims to verify the efficacy of conventional endotracheal tubes (PVC) and polymer-coated tubes in combating ventilator-associated pneumonia (VAP) in patients ventilated for more than 48 hours. Thus, after observing the statistical graphs, we found that the coate [....] » Read More
Candida duobushaemulonii is a yeast that belongs to the Candida haemulonii species complex. Similar to Candida auris which is an emerging global health threat, C. duobushaemulonii is a major concern in the healthcare system as it is often multidrug resistant. Prese [....] » Read More
Leishmaniases represent a major public health problem not only because of the number of cases recorded each year, but also because of the wide distribution of the disease. It is a parasitic disease caused by around 20 species of flagellated protozoa transmitted by the bite of [....] » Read More
The objective of the present study was to evaluate the antiviral properties of Thymoquinone (TQ), an active component of Nigella sativa, on avian infectious bronchitis virus (IBV) using embryonated eggs. 120 conventional embryonated eggs aged between 9 and 11 d wer [....] » Read More
Cultural beliefs and educational factors strongly influence intravaginal practices of women in Sub Saharan Africa. These behaviors appear common in different population across Africa. Previous research has suggested that vaginal douching modifies vaginal flora and was associated [....] » Read More
Pneumonia, the second leading cause of infant mortality in Côte d'Ivoire, remains unknown to the great one. Among the leading causes of environment-related child deaths, 570,000 children under 5 die from respiratory infections caused by indoor and outdoor air pollution [....] » Read More
Background: The use of medicinal plants as treatment options of human and animal diseases can be traced back in human history, and about ten percent of identified medicinal plants serve a pharmaceutical role because they have active chemical constituents such phenolic acids, flav [....] » Read More
The consequences of hepatitis C virus infection (HCV), a curable disease, are a major problem for the survival of the world's population, particularly in Africa. Over the decades, hepatitis has been viewed differently in various African countries, but the common denominator w [....] » Read More
This academic abstract offers an in-depth exploration of the journey toward implementing the Pharmacy Initiated Management of Antiretroviral Therapy (PIMART) initiative while also considering the potential benefits of integrating digital health e-prescription processes via teleme [....] » Read More
Background: HIV prevalence amongst adults aged 15 and above in Zambia was 11.0% (ZAMPHIA 2022). Prevalence of viral load suppression amongst adults aged 15 and above living with HIV in Zambia was 86.2% at Sinda Zonal Health Centre by 2022. However, because of this burden, combine [....] » Read More
Background: COVID-19 has shown to put people living with HIV (PLHIV) at a higher risk of catastrophic consequences and mortality. Research suggests that PLHIV who contract Corona virus (SARS-CoV-2) are more likely to require hospitalization and have poor clinical outcomes th [....] » Read More
The continuous drug resistance in parasites against the majority of the front-line antimalarials has resulted in countless deaths in malaria-endemic countries, with an estimated 619,000 deaths in 2021. Notably, the recent malaria outbreak during 2020–21 at Attapeu (Laos) ca [....] » Read More
Since the discovery of Double Helix by Watson and Crick in 1953 and its advancement in medicine, environment, unit operational bioreactor design, used in vaccine development and food. The application of nanotechnology and biotechnology are also being potentially used in processin [....] » Read More
Background: Terrestrial mammals in protected areas have been identified as a potential source of antimicrobial-resistant bacteria. Studies on antimicrobial resistance in gorillas have already been conducted. Thus, this study aimed to describe the phylogroups, pathotypes and preva [....] » Read More
Will be Updated Soon...
Some researchers have investigated the effects of different strains of rabies virus in in vitro, but the effects of nature circulating rabies virus have not been investigated in in vivo. Following cell infection, the virus takes over endoplasmic reticulum(ER), in order to deal wi [....] » Read More
There are many infectious diseases in Iraq due to difficult circumstances and wares occurred previously. Most of these disease are very dangerous for humans and animals and also effect the economic state in Iraq and may be extend to the niebouring countries. The infectious [....] » Read More
Spatial data modeling can provide significant value to healthcare organizations by improving decision support, resource management and distribution, and clinical outcomes. The aim of this study was to (i) summarize the trends of the modeling techniques used to analyze point-refer [....] » Read More
Objective Panton-Valentine leukocidin (PVL)-positive methicillin-resistant Staphylococcus aureus (MRSA) is a healthcare problem worldwide. There are no reports on the virulence characteristics of MRSA in Northern Cyprus (NC). This study aimed to determine the presence of pvl amon [....] » Read More
Introduction: Patients with undiagnosed pulmonary TB act as reservoirs for transmission and will result in 10-15 secondary infections in 1-5 Yrs. Health seeking behavior plays important role in early diagnosis and prompt treatment in TB care. Identification of factors influencing [....] » Read More
Introduction: A parasite may look docile and harmless but it can create havoc in human eyes. Early detection and timely treatment can prevent blindness. We report three cases of parasites in the eye with varying presentations. Case 1: A 76-year-old gentleman, a pet lover and a [....] » Read More
Bats carry thousands of viruses from 28 different families. To determine the presence of various pathogens in bat populations in Kazakhstan, 1149 samples (393 oropharyngeal swabs, 349 brain samples, 407 guano) were collected. The samples were collected from four species of bats ( [....] » Read More
Background: Dengue virus infection is caused by a positive stranded RNA virus called Dengue virus, which is spread by arthropods. It is a fast growing acute febrile disease with potentially lethal consequences that is a global public health problem, mostly in tropical and subtrop [....] » Read More
Background and aim: Data on the associations of vitamin D levels with severe outcomes of coronavirus disease 2019 (COVID-19) among critically ill elderly patients are not conclusive and also no information is available about some outcomes such as delirium. Therefore, the current [....] » Read More
Introduction: The presence of an untreated STI significantly increases the chance of acquiring HIV. In Brazil, CT/NG testing among PrEP users is insufficient and syndromic treatment is a priority in clinical practice. Multi-site testing for CT/NG improves screening of asymptomati [....] » Read More
Aim: Diabetic nephropathy (DN) is considered as one of the diabetic complications affectingup to 40% of patients with type 1 or type 2 diabetes. In clinical practice, the frequentlyused markers of renal disease and progression are serum creatinine, estimated glomerular filtration [....] » Read More
Human Immunodeficiency Virus creates disruption in the lives of individuals, families, organisations, and communities at large. The introduction of the antiretroviral treatment brought hope but also brought challenges, especially around the issue of adherence which is important f [....] » Read More
Background: In Nepal significant increase of zero dose children from1% to 4% have alerted all the stakeholders associated with child immunization1. In addition to this increasing outbreak of vaccine preventable diseases in the areas with low vaccination dose are showing importanc [....] » Read More
Background: Hepatitis B virus (HBV) is associated with several acute and long-term complications and vaccination is the cornerstone of prevention. A recent outbreak in Gulu, Uganda, one of the districts covered by a mass vaccination campaign, suggests low uptake of HBV vacc [....] » Read More
Background: Hepatitis B virus vaccination plays a crucial role in preventing Hepatitis B infection, particularly in high-risk groups such as children under-five, who have a 60-90% higher chance of seroconversion. As per the World Health Organization (WHO), about 5–10% of in [....] » Read More
Background: Despite increments in immunization coverage over the past decades, substantial inequality due to wealth status has persisted in Ethiopia. This study aimed to decompose the concentration index into the individual factors contributing to socioeconomic-related inequaliti [....] » Read More
Visceral leishmaniasis caused by Leishmania are pathogenic protozoans that primarily attack mammalian macrophages, dwells within it as intracellular parasite requiring iron (Fe) from host. Host iron acquisition by Leishmania spp. is crucial for DNA replication, mitochondria [....] » Read More
Mycobacterium tuberculosis (Mtb) is the oldest pathogen of the mankind, responsible for the Tuberculosis (TB) disease in humans. TB infection is the leading cause of morbidity and mortality accounted by a single pathogen. Despite all the efforts to develop a new vaccination strat [....] » Read More
Dirofilaria immitis and Dirofilaria repens are mosquito-borne nematodes which infect primarily dogs as their main definitive hosts. They cause cardiopulmonary (D. immitis) or cutaneous (D. repens) dirofilariasis in canids and other carnivores and can accidentally be transmitted t [....] » Read More
Background: Metallo-beta lactamase resistance is one of the carbapenem resistances that worsen the world nowadays. A new variant of carbapenem-resistant has only limited reports from Africa including Ethiopia. This study aimed to determine Metallo -ß- lactamase resistance G [....] » Read More
Tobacco Prevention and Control Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Background: Few studies have shown that smokers are more likely than nonsmokers to contract COVID 19, wh [....] » Read More
In hospitals, yeast of the genus Candida species albicans has played an important role in infections for over two decades. It is the fourth most common cause of septicemia in the USA and seventh in Europe. In terms of seriousness, it is associated with a high mortality rate, espe [....] » Read More
The incidence of mycoses caused by Candida spp. has increased steadily over the past two decades, Candida albicans remains the most commonly isolated microscopic fungus. The objective of our study was to identify the profile of a few strains of Candida albicans isolated from diff [....] » Read More
Introduction: Leishmania is a common zoonotic parasite that cause leishmaniasis which has been recognized as a global issue in 98 countries. One of the most reliable methods to diagnose disease is parasite culturing, the most common media used are NNN and RPMI1640 but these media [....] » Read More
Introduction: Cutaneous leishmanisis is a parasitic disease which is transmitted by sand fly to human, affects lots of people in all over the world that has a great burden on societies and people. Cutaneous leishmaniasis standard treatment is injection of pentavlant antimoniate [....] » Read More
A flagellate protozoan, Giardia duodenalis (or Giardia intestinalis, formerly Giardia lamblia), causes human giardiosis. It is the most widespread intestinal parasitosis in the world. This work involved all patients clinically suspected of suffering from giardiosis or other [....] » Read More
Tuberculosis (TB) is a deadly disease that is difficult to treat. Existing drugs are not always effective, and new drugs are needed. Drug repurposing has become a popular approach for drug discovery due to the advancements in high throughput computational screening methods. [....] » Read More
Entomological monitoring is seen as a crucial activity involving the systematic collection, analysis, and interpretation of entomological data for planning, implementation, monitoring, evaluation, and decision-making. The National Malaria Elimination Program (NMEP) of the Ghana H [....] » Read More
Introduction: Tetanus is an acute disease caused by a powerful neurotoxin produced by the bacterium Clostridium tetani manifested by skeletal muscle spasm and autonomic nervous system disturbance. It is and is completely preventable by vaccination. In 2017, that the Philippine go [....] » Read More
Antimalarial drug resistance is a major global challenge and a leading cause of death among children under 5-year and pregnant women. The study aims to investigate the combinatorial effect of an African Indigenous Plant extract and Amodiaquine on Plasmodium parasite infection in [....] » Read More
Newcastle disease (ND) is a highly contagious and transboundary disease that affects a wide range of avian species. The outbreaks of deadly diseases that affect commercial chicken flocks are mostly caused by it, They cause large annual economic losses for the industry and still b [....] » Read More
The increase in the transfer of pathogenic microorganisms between humans, livestock, wildlife and their environment observed in recent years, as well as the irrational use of antibiotics, makes it increasingly difficult to combat the growing multidrug resistance of bacteria such [....] » Read More
Introduction: The World Health Organization (WHO) and the Global Health Security Index (GHSI) reported a lack of biosecurity and biosafety capacity and practice across the Middle East and North Africa (MENA) region. Private human and animal diagnostic laboratories in Egypt play a [....] » Read More
Background: As of 2020, 71.5% of tuberculosis (TB) cases in the United States occur in foreign-born patients.1 Gaps in healthcare, congregate living conditions, are just some of the challenges that immigrants and refugees from high incidence countries face that make them especi [....] » Read More
We present a case of West Nile Virus Encephalitis .West Nile fever is an infection by the West Nile virus, which is typically spread by mosquitoes. WNV is one of the Japanese encephalitis antigenic serocomplex of viruses.In about 80% of infections people have few or no symptoms. [....] » Read More
South Africa has one of the highest prevalences of Human Immunodeficiency Virus (HIV) globally. Since the emergence of SARS-CoV-2, which causes Corona Virus Disease 2019 (COVID-19), South Africa’s population has suffered from both high infection and mortality rates. Many st [....] » Read More
Hepatitis B (HBV) and C (HCV) are two among other forms of infections for which co-infection in HIV has been associated with alteration of the immune response, increased risk of progression to liver diseases and increased risk of hepatotoxicity associated to antiretroviral therap [....] » Read More
Background: Staphylococcus aureus is an opportunistic pathogen which is responsible for various infections when ingested. This study was carried out to determine the prevalence of methicillin resistant Staphylococcus aureus from edible vegetables sold in Minna, Niger state, [....] » Read More
Antimicrobial resistance is a major threat to global health, and primarily occurs due to the overuse of broad-spectrum antibiotics. If not addressed, we are headed towards a post-antibiotic era. To address this issue, in 2015, the World Health Organisation developed a Global Acti [....] » Read More
COVID-19 type virus infection in a group of individuals results from the uptake by the lungs of these individuals of virions from the local atmosphere created by infected members of the group. The concentration of virions is determined by the social activity of group members and [....] » Read More
A robust progress in the field of structural biology has allowed the scientists to see the architectural beauty of the macromolecules along with their dynamics. The variety of resolution comprehends by different techniques allow to observe the changes in the macromolecules over t [....] » Read More
Introduction: Considering the importance of ceftazidime/avibactam (CAZ/AVI) and polymyxin B (PMB) in treating carbapenem-resistant Klebsiella pneumoniae (CRKP) infection, it is essential to evaluate the efficacy and safety of these agents and provide appropriate medical advice to [....] » Read More
In 2016, according to the United States Centers for Disease Control and Prevention (CDC), and Public Health England, Candida auris, has been labeled as an emerging multidrug-resistant (MDR) yeast. Despite causing significant mortality, there are still no available Minimum inhibit [....] » Read More
Background: Salmonella species and Escherichia coli are important foodborne pathogens affecting humans and animals. They are among the most important causes of infection that are associated with the consumption of contaminated food. This study was aimed to determine the prevalenc [....] » Read More
Introduction: Disseminated tuberculosis is a severe form of the disease involving two or more non-contiguous body sites or blood or bone marrow concurrently.The diagnosis and management often pose a challenge due to varied clinical presentations. Case Report: We report a case [....] » Read More
A 56-year-old male with end-stage renal disease undergoing home peritoneal dialysis presented with abdominal pain, nausea, and altered mental status. White blood cell count was 12.3 10e3/uL, urinalysis was positive for 2+ blood, and peritoneal fluid contained a total nucleated ce [....] » Read More
Background: The World Health Organization (WHO) estimated the global incidence of syphilis among adults to be approximately 7.1 million in 2020. The following year, the American Centers for Disease Control and Prevention (CDC) reported a 32% increase in the incidence of primary/s [....] » Read More
Relatively, vaccination is a new way of preventing infectious diseases. The main its target is training the body to be ready for the real pathogenic infection. According to a simplified definition, it is a process of infecting the body with a modified/artificial pathogen/antigen. [....] » Read More
The COVID-19 pathogen is a pathogen with a single strand of genetic material, belonging to the family coronaviridae. It possesses a genome that is approximately 29881 bp long, which results in the development of a respiratory disease with sudden onset. One of how the COVID-19 vir [....] » Read More
There are currently an estimated 39.0 million people living with HIV around the world. Sexually transmitted infections, also known as STDs, continue to be a major public health challenge in developing countries. The prevalence of STIs, including bacterial (Chlamydia trachomatis, [....] » Read More
Background: Patients with acquired immunodeficiency syndrome HIV disease can present with a constellation of symptoms and syndromes. In this abstract we describe a rare case of human herpesvirus 8 (HHV-8) apparently unrelated and not multicentric Castleman disease (CD), as the pr [....] » Read More
A 53 year old female presented with reddish raised lesion over left anterior shin for 3 years which eventually ruptured into ulcer, lesion gradually increased in size, purulent discharge from ulcer. Patient had similar compliants 2 years back wound debridement was done outs [....] » Read More
A 50 year old male admitted with complaints of left sided chest pain for 15 days, dull aching type, history of shortness of breath on exertion for 15 days, no history of previous similar complaints and no previous history of Pulmonary Tuberculosis, no other associated comorbiditi [....] » Read More
A 35 year old male admitted with complaints of cough with expectoration for 3 weeks, which is mucoid in consistency, sometimes blood tinged, history of evening rise of temperature for last 14 days, history of loss of weight and loss of appetite present, no history of pervious sim [....] » Read More
The patient, a 37 year old non-smoker and occasional alcoholic, presented with a three-week history of cough, blood-tinged expectoration, evening fevers, weight loss, and loss of appetite. There was no previous history of Pulmonary Tuberculosis. Notably, the patient had irregular [....] » Read More
Title : Ultrasound for diagnosing pneumonia. The place of the BLUE-protocol
Daniel A. Lichtenstein, Ambroise Pare Hospital, France
The BLUE-protocol is an ultrasound approach of lungs and veins, allowing with fine accuracies an immediate diagnosis of an acute respiratory failure among the six causes which regard 97% of patients seen in critical settings: hemodynamic pulmonary edema, pulmonary embolism, [....] » Read More
Title : Hemophagocytic lymphohistiocytosis syndrome and syndrome of inappropriate antidiuretic hormone ADH release: keep in mind visceral leishmaniasis. Case report and literature review
Daniela Tirotta, Morgagni - Pierantoni Hospital in Forlì, Italy
Introduction. Visceral leishmaniasis is an potentially fatal and neglected tropical disease, according to the World Health Organization’s : mortality is still very high ( 95% ) when untreated. This disease presents a broad spectrum of symptoms (oligosymptomatic infection, b [....] » Read More
Title : Validation of the normandy score- Predictive of abnormal echocardiography- in the management of bacterial native joint and bone infections
Marie Beaufrere, Paris-Saclay University, France
Introduction. Native joint and bone infections (NJBI) are frequently associated with infective endocarditis (IE). Normandy score, based on the patient's valvular assessment, the bacterial species and the hematogenous mechanism of NJBI was published to guide the prescription o [....] » Read More
Title : Using mathematical models to explore future meningitis vaccination strategies in Ghana
Mark Asare Owusu, University of Cambridge, United Kingdom
The African meningitis belt, a region which stretches from Senegal to Ethiopia including Ghana, has experienced irregular but periodic epidemics of meningitis, primarily due to Neisseria meningitidis for over a hundred years. The introduction of MenAfriVac, a conjugate vaccine wh [....] » Read More
Title : HHV6 encephalitis in an immunocompetent host
Ahmed Esam Mahboub, Tawam Hospital, United Arab Emirates
Introduction: A previously healthy and a fully vaccinated 5-year-old pre-schooler-aged male who presented to the ER with an insidious onset of decreasing level of consciousness and headaches before developing Status Epilepticus, and requiring admission to the PICU; with a final [....] » Read More
Title : Triple threat: Severe COVID-19-strongyloidiasis-taeniasis co-infection: A case report
Helen Jane Polido, Baguio General Hospital and Medical Center, Philippines
Strongyloidiasis is caused by a soil-transmitted threadworm that is endemic worldwide and is more prevalent in humid climates. Taeniasis on the other hand, is an intestinal infection with tapeworms which is usually acquired by ingestion of parasite’s larval cysts in underco [....] » Read More
Title : Double Trouble: Co-infection with Cryptococcal Meningitis and Japanese Encephalitis
Golden Tamon-Gayo, Baguio General Hospital and Medical Center, Philippines
Background: Cryptococcal meningitis (CM) is the most common central nervous system infection (CNSI) among patients with severe immunodeficiency syndrome secondary to human immune deficiency virus. Co-infection with other CNSI is relatively common especially with TB meningitis and [....] » Read More
Title : IL-27 as a biomarker for distinguishing between necrotizing enterocolitis and highly suspected early-onset food protein-induced enterocolitis syndrome
Yaun Shi, Children’s Hospital of Chongqing Medical University, China
Background: The initial clinical manifestations and abdominal imagines of neonates with necrotizing enterocolitis (NEC) and food protein-induced enterocolitis syndrome (FPIES) are sometimes similar, however, their prognosis and therapies are different. We aimed to evaluate the ut [....] » Read More
Title : Antiretroviral resistance among HIV-infected patients in the upper southern region of Thailand
Siwimol Phoomniyom, The Office of Prevention and Disease Control 11th Region, Thailand
The trend of HIV infected people in Thailand has been declining since 2000. Owing to the Thailand's National Access to Antiretroviral Program for People who have AIDS (NAPHA) program promoting access to antiretroviral drugs, the use of antiretroviral drugs has been widespread [....] » Read More
Title : Unraveling potential early diagnostic biomarkers of opisthorchis viverrini infection through comparitive immunoproteomics of the sera of infected mice and hamsters
Alok Kafle, Khon kaen University, Thailand
Opisthorchiasis, caused by Opisthorchis viverrini, continues to pose a significant public health challenge, particularly in the Lower Mekong Basin of Southeast Asia, necessitating urgent attention and intervention. Research on O. viverrini has primarily focused on proteomic and t [....] » Read More
Title : Fight against measles and rubella in Morocco: Evaluative study
Kharti Kawtar, doctoral study center-Ibn Tofail University, Morocco
Like other countries in the Eastern Mediterranean region, Morocco is committed to eliminating measles and rubella in order to reduce infant and child mortality. The objective of this study is to evaluate the National Immunization Program reinforced against these two diseases in M [....] » Read More
Title : Clinical and etiological features of infectious uveitis in HIV-positive and HIV-negative patients in the department of internal medicine
Jait Nissrine, IBN SINA University Hospital, Morocco
Introduction: Uveitis is an inflammation of the uvea, intraocular, of heterogeneous etiology and presentation. The aim of our study is to describe the clinical and therapeutic features of infectious uveitis in HIV+ and HIV- patients. Patients and methods: This is a retrospecti [....] » Read More
Title : Interest of CAP (controlled attenuation parameter) in screening for hepatic steatosis in HIV monoinfected patients
Jait Nissrine, IBN SINA University Hospital, Morocco
Introduction: Patients living with HIV (PLHIV) are at high risk of developing hepatic steatosis, even in the absence of HBV/HCV co-infection, due to chronic HIV infection, lifelong use of antiretroviral drugs (ARVs) and the frequency of co-morbidities such as overweight, diabetes [....] » Read More
Title : Acute complications of Covid-19 infection in pregnant woman during the period 2020-2021
Fatiha Hachani, Kasdi Merbah University, Algeria
Introduction: In December 2019, a new coronavirus identified in Wuhan, China was responsible for the rapid emergence of COVID-19, declared by the WHO a global pandemic in March 2020, responsible for a high rate of mortality and occurrence of acute and long-term complications. [....] » Read More
Title : Impact of an Antibiotic Stewardship Program ( ASP) on antibiotic use, bacterial susceptibilities, and cost of antibiotics: A quasi-experimental study from a developing country
Banan Muneer Aiesh, An-Najah National University Hospital, State of Palestine
Antimicrobial misuse is a worldwide issue, and antimicrobial resistance is considered one of the most challenging aspects of health care. It has been reported that as much as 30%–50% of antimicrobials prescribed in hospitals are unnecessary or inappropriate. Antib [....] » Read More
Title : Intestinal helminths in a population of children from the Kashmir valley, India
Showkat Ahmad Wani, Sri Pratap College, India
In any geographical area, surveys of the prevalence of intestinal helminths are necessary to suggest appropriate control measures. The aim of this study was to determine the prevalence of intestinal helminth infections in children of the Kashmir valley and to identify the risk fa [....] » Read More
Title : Containment of an outbreak in Critical Care (ICU): An incident report of a multispecialty hospital in developing world
Raman Sharma, Post Graduate Institute of Medical Education And Research, India
Introduction: Varicella-zoster virus (VZV) infection in healthcare organisations, especially in ICUs, is of serious concern, primarily having admitted critical and immunocompromised patients. Methodology and Results: The report defines the transmission and infection control [....] » Read More
Title : Structured TB risk factors in regions with high and low population density in Russia
Zinaida Zagdyn, Semashko National Research Institute of Public Health in Moscow, Russian Federation
In Russia, with increase in life standard and following it improvement in the TB epidemic situation, socio-demographic, health care managing, climatic and environmental TB risk factors, such as population density, intensity of social contacts, availability of medical care, season [....] » Read More
Title : Virus/mutation-agnostic vaccines
De chu Christopher Tang, VaxDome Inc., United States
Respiratory RNA viruses often mutate into new variants with subsets ravaging public health as escape mutants that render contemporary vaccines and antivirals ineffective from time to time. We have serendipitously developed an innovative approach to vaccine development against res [....] » Read More
Title : A rare case of purulent massive pericardial effusion in an 85-year-old male
Ira Vori Nugroho, Universitas Brawijaya Malang, RS Dr. Saiful Anwar Jawa Timur, Indonesia
Introduction: Purulent pericarditis is defined as an infection in the pericardial space that produces macroscopically or microscopically purulent fluid.1 It was a rare but life-threatening condition.2 It may be primary or secondary to another infectious process. There are five pa [....] » Read More
Title : Implementing the Covid-19 vaccination programme in the Southwest of England: Lessons from a normalisation process theory perspective
Anne Morris, North Bristol NHS Trust, United Kingdom
Background: Vaccination remains one of the most successful public health interventions in preventing severe disease and death. The roll-out of Covid-19 vaccination programmes has helped protect billions of people around the world against Covid-19. Most of these programmes have be [....] » Read More
Title : Comparative evaluation of pathogens in Saiful Anwar Hospital's CVCU vs. Indonesian ICUs: A focus on hospital-acquired Infections
Gallusena Erickatulistiawan, Brawijaya University – Saiful Anwar Hospital Malang, Indonesia
This study investigates the patterns of hospital-acquired infections, specifically analyzing bacterial isolates from a variety of clinical samples collected in the Intensive Cardiovascular Care Unit (CVCU) at Saiful Anwar Hospital in Malang, Indonesia, during the year 2022. This [....] » Read More
Title : Abrupt and lethal rare complication: A case report of a 32 year-old male who suffered from pyogenic ventriculitis
Alexis Torres Rodriguez, Universidad Central del Caribe Internal Medicine Residency, Puerto Rico
Introduction: Pyogenic ventriculitis is characterized by ependymal lining inflammation of the cerebral ventricular system and presence of suppurative fluid in the ventricles. Risk factors include a compromised immunity such as human immunodeficiency virus, diabetes, and cancer. T [....] » Read More
Title : The next frontier in malaria prevention: Pfs230D1 transmission-blocking vaccine’s novel surrogate assay of efficacy
Cristina Meehan, National Institutes of Health, NIAID, United States
In 2023, malaria impacted 247 million individuals across 85 countries, resulting in 619,000 global deaths. The international focus to develop a higher efficacy malaria vaccine is a top priority, yet the complex parasite lifecycle poses a significant challenge to vaccine developme [....] » Read More
Title : Use of Intravenous Immunoglobulin in Neonatal Enteroviral Sepsis
Melanie Rosado, University of Utah, United States
A 4-day-old term infant with a low EOS risk score originally presented to the ED with six hours of lethargy and poor feeding. Initial work-up was demonstrated acute liver failure (PT/INR 18.5, ALT>90, AST>300), hypoglycemia, hyperferritinemia (ferritin >44,000), severe t [....] » Read More
Title : Use of intravenous immunoglobulin in neonatal enteroviral sepsis
Michele de Leon Jauregui, University of Utah, United States
A 4-day-old term infant with a low EOS risk score originally presented to the ED with six hours of lethargy and poor feeding. Initial work-up was demonstrated acute liver failure (PT/INR 18.5, ALT>90, AST>300), hypoglycemia, hyperferritinemia (ferritin >44,000), severe t [....] » Read More
Title : Prevalence of covid-19 diagnosis among Brazilian nurses after complete vaccination schedule
Elucir Gir, University of Sao Paulo, Ribeirao Preto College of Nursing, Brazil
Introduction: Facing the COVID-19 pandemic caused damage to the physical health of nurses, especially those who worked on the so-called front line, as they were exposed to constant risks of contamination, exhaustive workload and difficulties in the availability of inputs, such as [....] » Read More
Title : Prevalence of physical and/or mental health symptoms for four weeks or more due to covid-19 among Brazilian nurses
Elucir Gir, University of Sao Paulo, Ribeirao Preto College of Nursing, Brazil
Introduction: Long COVID comprises a complex, multidimensional, progressive and impactful syndrome characterized by the persistence of residual symptoms after the initial COVID-19 infection, without an alternative diagnosis or associated condition. Objective: To identify the p [....] » Read More
Title : The presentation of rhabdomyolysis in influenza B patients – a case series
Simona Yoffe Deri, sheba hospital, Israel
Influenza B-associated rhabdomyolysis is relatively rare. Herein, we describe a retrospective case-series of five children hospitalized in a single institution for rhabdomyolysis from PCR-confirmed Influenza B. Viral sequencing revealed a novel deletion of one amino acid in the v [....] » Read More
Title : Early versus Late Onset Necrotizing Enterocolitis in Very Low Birth Infants in the Neonatal Intensive Care Unit
Simona Yoffe Deri, sheba hospital, Israel
Background: Necrotizing Enterocolitis (NEC), one of the most severe emergencies in neonates, is a multifactorial disease with diverse risk factors. Objectives: To compare between the clinical and laboratory characteristics of premature infants diagnosed with early-onset NEC (E [....] » Read More
Title : Risk Factors, Sensi0vity Pa4ern and Clinical Outcomes of Candidemia among Pa0ents Receiving Parenteral Nutri0on Admi4ed at St. Luke’s Medical Center
Maria Florabel P. Buenaflor, St. Luke's Medical Center, Philippines
Candidemia is often associated with high rates of morbidity, mortality and long hospital stays especially on critical ill patients. Parenteral nutrition is an established risk factor in developing candidemia. Since there are limited local studies on candidemia in parenteral nutr [....] » Read More
Title : Dynamics of SARS-CoV-2 shedding in the nasopharyngeal samples in hospitalized COVID-19 patients
Liu Yen Hung, Cardinal Tien Hospital, Taiwan
Introduction: SARS-CoV-2 has spread worldwide and dramatically and devastatingly impacted our society. Quarantine has been taken to slow down its spread. Due to some adverse impacts on individuals and communities caused by quarantine, other interventions, such as vaccination and [....] » Read More
Title : The extended RD1 region protein EspG1: Its role in mycobacterial virulence and pathogenicity
Prachi Urade, National Centre for Cell Science, India
Tuberculosis (TB), caused by Mycobacterium tuberculosis, is one of the deadliest diseases worldwide. The major challenge to the existing TB treatment is the emergence of Multidrug Resistant (MDR) M. tuberculosis which limits the success rate of treatment and therefore generating [....] » Read More
Title : A cohort study of the spectrum of coagulopathy in acute sepsis and its correlation with physiological scores and outcome
Aishwarya Vyas, SMS Medical College, India
Purpose: To evaluate the spectrum of coagulopathy in acute sepsis and to correlate it with sequential physiological scores (SOFA & APACHE II) and compare the findings among survivors and non-survivors. DESIGN: Prospective cohort Methods: It is a prospective c [....] » Read More
Title : Antiviral activity of different molecules obtained from invertebrates against coronavirus
Zucatelli, Instituto Butantan, Brazil
Introduction: The coronavirus has become known because of the COVID 9 pandemic. Coronaviruses cause epidemics not only in humans, but also in animals of commercial interest such as birds (Infectious bronchitis virus-IBV). This virus has a replication mechanism similar to the huma [....] » Read More